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is plasma contain glutathione Cellular Compartmentalization, Transport and Its Relevance in Some Pathologies The ascorbate–glutathione cycle coming of
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doi: 10.13075/ijomeh.1896.01275

This suggests that PET46 may employ a different substrate-binding pattern, potentially involving the lid domain in the formation of the aromatic clamp (Burgin et al., 2024)

10.1080/15548627.2019.1596481 35 HeZ.GuoL.ShuY.FangQ.ZhouH.LiuY.et al (2017)

Based on the displayed structures, and in particular with that of the glutathione conjugate of etacrynic acid [132], which is itself a Michael acceptor, it is well conceivable that glutathione acrylate can dock into the glutathione activating pocket of the GST enzymes and irreversibly bind to the essential tyrosine phenolate function, thus inactivating the enzyme

doi: 10.1167/iovs.16-19686

and Wigglesworth, L
