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Yes, and this is very common

Signs concentration is optimal Gradual, steady improvement over time indicates your concentration is working effectively

Avram VF, Chamkha I, sander-Frostner E, Ehinger JK, Timar RZ, Hansson MJ, Muntean DM, Elmr E (2021) Cell-permeable succinate rescues mitochondrial respiration in cellular models of statin toxicity

Babaliari, E., Ranella, A

[DOI] [PubMed] [Google Scholar] Storozhenko S., Belles-Boix E., Babiychuk E., Hrouart D., Davey M.R., Slooten L., Van Montagu M., Inz D., Kushnir S

Assessing mitochondrial DNA release into the cytosol and subsequent activation of innate immune-related pathways in mammalian cells