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FGF21 (NCT03976401), FGF19 (NCT03912532), obeticholic acid (NCT01265498, T02548351), pioglitazone (NCT00994682, NCT00063622, NCT00062764, CT00227110), semaglutide (NCT02970942), and resmetirom (NCT02912260) had significant effects on NASH patients (Table 2)

And its not unusual for someone on these drugs to lose 10-20% of their body weight

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Retatrutide dose compared to tirzepatide and semaglutide Comparison is inevitable

doi: 10.1210/endo.136.8.7628397 53 OhnumaKUchiyamaMYamochiTNishibashiKHosonoOTakahashiNet al

Storage, Handling, and Safety Precautions Storage and handling requirements for retatrutide are defined solely by the trial sponsor's protocol