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FDA received another adverse event report on February 4, 2019, associated with an intravenous injection of a drug containing L-glutathione 200mg/mL compounded by a different pharmacy that also

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Subsequently, basic research on GSH in the CNS has been focused on therapeutic strategies aimed at reducing neurodegeneration, and a drug increasing GSH levels in the brain would be promising as a disease-modifying drug characterized by neuroprotective effects

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592,593 Moreover, due to the decrease of 3-hydroxykynurenine (a cytotoxic metabolite of KMO), the mice that lack active kynurenine 3-monooxygenase (KMO) will not develop into AKI after I/R injury