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Based on these data, specific oral pathobionts presumably play vital roles in the development of inflammatory disorders through LGS ( Figure 1 )

however, avoid high-dose green tea extract supplements , which have been associated with liver injury Oily fish (salmon, mackerel, sardines) offering omega-3 fatty acids with anti-inflammatory effects Whole grains containing selenium and various antioxidant compounds A Mediterranean-style diet , which is naturally rich in antioxidants from olive oil, vegetables, fruits, nuts, and fish, has shown particular promise for NAFLD in clinical studies

Similarly, in dendritic cells benfotiamine suppressed the release of proinflammatory cytokines TNF- and IL-1 and prevented translocation of NF-B to the nucleus [86]

doi: 10.1053/j.gastro.2019.06.048 91

The gut contributes to the maintenance of the defense and repairs the gastrointestinal mucosa [33]
MARTX toxin of Vibrio vulnificus induces RBC phosphatidylserine exposure that can contribute to thrombosis