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Acknowledgements This work was supported by grants from the National Research, Development and Innovation Office (NKFI-FK123798, NKFI-K 134555, Nemzeti Kardiovaszkularis Laboratorium), the Hungarian Academy of Sciences Bolyai Research Scholarship (to PT), the National Institute on Aging (RF1AG072295, R01AG055395, R01AG068295

Reviews of BPC-157 biology describe interactions with nitric-oxideassociated signaling systems and vascular regulatory pathways that influence cellular adaptation to metabolic or oxidative stress [1][6][11]