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In nutrient-rich conditions, mTOR remains active, suppressing autophagy initiation, while under stress conditions such as energy deficiency or DNA damage, the activation of AMP-activated protein kinase (AMPK), p53 or inhibition of pathways like PI3K/Akt and ERK reduces mTOR activity, which then releases the inhibition on autophagy and facilitates its initiation (Yang and Klionsky, 2010)

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Kim, J.-H., Studer, R., Vo, N., Sowa, G

Expression of glycosaminoglycans and small proteoglycans in wounds: modulation by the tripeptidecopper complex glycyl-l-histidyl-l-lysine-Cu2+

Manages Pigmentation: It influences melanin production, which may help regulate skin tone and manage pigmentation concerns for a more even complexion