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Clinical trials showed that exogenous BDNF had limited success as therapeutic, mainly due to suboptimal pharmacokinetic properties and side effects

Cerebrovascular and metabolic effects on the rat brain of focal Nd:YAG laser irradiation

In this study, we successfully achieve tumor-targeted aggregation of an aggregation-induced emission photosensitizer (AIE-PS), TB m A, with the catalysis of a tumor-overexpressed enzyme, -Glutamyl Transferase (GGT)
10.1016/j.jmb.2004.12.003 286

These three major areas have shown a reduction in wrinkles and inflammation, an increase in skin firmness, and an overall more even tone

The basic science makes sense and is why theres interest in exploring KPV to help with inflammation, gut health, and skin support
