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In the context of diabetes, chronic hyperglycemia overwhelms the mitochondrial electron transport chain, leading to increased ROS production [176]

Going to bed late means less time for cell recycling and DNA damage repair
Taken together, these trends suggest that a host-specific AAA derivative is less likely to be present in the caecal contents than a derivative that could form through reactions present in the microbiota
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doi: 10.1021/jacs.5b12070
