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Transamination Reactions: Glutamate can also be converted to -KG through transamination with aspartate by the action of aminotransferases, which transfers the amino group to oxaloacetate, producing -KG

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It is important to point out that NICE Guidelines also advise a wide range of non-pharmacological procedures including education [energy conservation], exercise [aerobic, resistance and yoga], psycho-behavioural techniques [Cognitive Behavioural Therapy (CBT) or mindfulness programs such as tai-chi, yoga, relaxation and meditation] all of which have the potential to lead to significant improvements in MSRF

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