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JA is synthesized from fatty acids in three steps, starting in the chloroplast membrane

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J Clin Psychiatry 2007

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From Gene Lists to Redox Networks: The Rise of Systems Biology Moving beyond the identification of individual genes, systems biology enables researchers to model redox responses as emergent network behaviors

This site, called the catalytic site of the enzyme, has been evolutionarily structured to provide specific, high-affinity binding of substrate(s) and to provide an environment that favors the catalytic events