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Carvedilol treatment reduces transthyretin deposition in a familial amyloidotic polyneuropathy mouse model

145 Telaglenastat, a glutaminase inhibitor, was also evaluated in combination with everolimus (TelaE) in a phase I trial of advanced/metastatic renal cell carcinoma (mRCC), and TelaE therapy was well tolerated in patients previously treated with TKIs and checkpoint inhibitors (NCT03163667)

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His ex vivo experiments consisted of filling the mouth ulcer of a diseased patient with hydrogen peroxide

Strengthening interdisciplinary collaboration might promote the research and development of NDDS

Clearly, more study is needed to help us understand these and other aspects of detecting and managing DILI in the clinic as well as in drug development, and is the focus of this Research Topic