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Skeletal growth acceleration with growth hormone secretagogues in transgenic growth retarded rats: pattern-dependent effects and mechanisms of desensitization

Grade I (mild sprain) Goals Control pain and swelling Restore knee range of motion (ROM) Begin muscle activation, particularly quads and hamstrings Gradually reintroduce load Typical plan Acute / protection phase (days 13 or until pain allows) Rest (avoid aggravating activities) Ice, compression, elevation Gentle passive / active assisted knee flexion/extension (within tolerance) Quadriceps sets (isometric contraction) Straight leg raises if pain allows Early rehab (week 12) Progress ROM (heel slides, wall slides) Light closed-chain loading (mini squats) Gentle hamstring activation Begin balance / proprioception (e.g

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