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Even though some enzymes have been identified as possible therapeutic targets, the intricate interactions between various pathways necessitate a more organized, multitarget, process-directed therapeutic approach that seeks to concurrently interfere with several oncogenic processes in order to reduce the number of potential escape mechanisms that tumors may use (120)

Leucine-rich repeat kinase 2 (LRRK2) is a large multidomain protein that plays a significant role in inflammation and neurotoxicity in autosomal dominant and sporadic forms of Parkinson's disease (Bentley-DeSousa et al., 2025[34])

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Prolongation of cardiac Allograft survival by endometrial regenerative cells: focusing on B-cell responses
