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Celastrol inhibits rheumatoid arthritis by inducing autophagy via inhibition of the PI3K/AKT/mTOR signaling pathway

(PubMed) Talbott MC, Miller LT, Kerkvliet NI

Cells were washed 3 times with PBS before detection of MitoSOX staining by flow cytometry

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Collagen deposition studies demonstrate the combination accelerates not only collagen synthesis but also improves fiber organization and structural integrity