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Ultimately, while a KD may be metabolically advantageous for many euthyroid individuals, those with subtle thyroid dysfunction or autoimmune diathesis require proactive management to prevent hormonal imbalances from emerging during prolonged carbohydrate restriction

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doi: 10.1073/pnas.97.8.4279

The specific transcriptional response of tumor endothelial cells is not only related to angiogenesis and vessel integrity, but may also affect endothelial activation and recruitment of leukocytes

The kit of any one of embodiments 29 to 38, wherein the heavy isotopologue of the maleimide is d5-NEM