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It seems that the efficacy of B9 supplementation is dose-dependent such that, the combination of 1 mg/d folic acid, 25 mg/d vitamin B6, and 400 g/d B12 during 6 months did not have any significant effect on serum homocysteine and symptoms of migraine (74)

These two factors are related because with IR, insulin cant efficiently transport sugar (glucose) from the blood into cells, resulting in elevated blood sugar levels

Side effects are usually mild and dose-dependent

No, at recommended doses L-carnitine is safe for the heart

It is not a stimulant

doi: 10.1186/1475-2891-13-110 8-) U Keller, C van der Wal, G Seliger, C Scheler, F Rpke and K Ederi, Carnitine status of pregnant women: effect of carnitine supplementation and correlation between iron status and plasma carnitine concentration