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Barnden, Leighton R

TF protected iRPE cells from sustained iron overload, which mimics GA features Iron accumulation is observed in the retina of AMD patients, and our clinical results suggest that an iron-TF imbalance favors iron overload toxic situation in GA eyes, which still have progression threat

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Scientists use the ratio between these forms to measure cell redox status

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This highly flexible arrangement facilitates simultaneous binding of several host endocytic proteins and modulation of the hosts PM (Fig