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For example, a translational study showed that ALDH2 suppression was protected by physiologically relevant levels of omega-3 polyunsaturated fatty acids [103, 211], and in a recent phase II clinical trial, treatment with clomethiazole (CMZ), an inhibitor of CYP2E1, mitigated the biomarkers of alcohol-induced oxidative stress and ALD progression [212]
By exploring the one-carbon cycle, the cornerstone of methylation (see Figure 1 ), we can comprehend how this biochemical process influences health and behavior [4]
Fortuo A, San Jos G, Moreno MU, Beloqui O, Dez J, Zalba G (2006) Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome
Food Bioproc Technol 7, 22812290
[DOI] [PubMed] [Google Scholar] Hochman A, Sternin H, Gorodin S, Korsmeyer S, Ziv I, Melamed E, Offen D
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