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The trial will respect all basic ethical principles of autonomy, justice, goodness of intent and absence of malintent according to the standards of good clinical practice enshrined in the Declaration of Helsinki (Seoul, 2008) and the Oviedo Agreement ( Convenio de Oviedo ) (1997)

Conclusion DPN represents a major and growing complication of diabetes, affecting both type 1 and type 2 populations, and increasingly observed in prediabetes

If redness persists for hours, spreads beyond the application area, or worsens over time, reduce concentration or frequency

Several devices use vibration at the ear canal, chest, or throat to activate parasympathetic pathways and raise HRV

Mucosal Glycan Foraging Enhances Fitness and Transmission of a Saccharolytic Human Gut Bacterial Symbiont