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This imbalance is further amplified by portosystemic shunting, which allows unmetabolized estrogens to bypass hepatic clearance, and by enhanced peripheral aromatization of androgens to estrogens in adipose tissue

In contrast, the mean apoptosis curve of the 29 MT-negative cases revealed higher sensitivity to the treatment, with the maximal apoptotic effect on the first day and completion of the apoptotic action on the sixth day

10.3389/fpsyg.2021.648691 7 AzarmiM.MalekiH.NikkamN.MalekinejadH

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10.1378/chest.129.1.118 24 BusseP
doi: 10.1111/1462-2920.13589 121 MagneF.GottelandM.GauthierL.ZazuetaA.PesoaS.NavarreteP.et al