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10.1002/jcp.22862 205

The endogenous glucocorticoids bind to the mineralocorticoid receptors with a 10-fold greater affinity than to the glucocorticoid receptors (79-81)
Because copper ions participate in numerous enzymatic reactions, the peptidemetal complex has been examined as a model for studying regulated copper trafficking and peptide-mediated metal transport

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347 After the development of first-generation SERMs tamoxifen and second-generation SERMs toremifene and raloxifene, several novel endocrine therapy drugs are currently under development to enhance efficacy and reduce toxicity
