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These particles can be further functionalized with ligands (e.g., peptides or antibodies) that target receptors highly expressed on specific lung cells involved in COPD pathogenesis, such as CD44 on alveolar macrophages

10.1016/j.schres.2009.03.005 Schizophr

All three methane synthesis pathways culminate in the formation of methyl coenzyme M, which is catalyzed by methyl coenzyme M reductase I (MCR I) and methyl coenzyme M reductase II (MCR II) with the ultimate formation of methane 45

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Conversely, a study by Zhao et al