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Osteoarthritis particularly may require long-term management given progressive nature

Journal of Medicinal Chemistry, 57 (22), 9220-9231

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A retrospective external validation set from an additional three European cohorts (n = 7,025), four Japanese hospitals (n = 281) and two hospitals from the USA (n = 1,437) was established

Research suggests a TB-500 dose of 2-5mg administered twice weekly for four to eight weeks

Note: Retatrutide is currently considered investigational and is not yet FDA-approved