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Increased melanin production and tanning MT1 binds strongly to the melanocortin 1 receptor (MC1R), which is involved in the production of melanin, tyrosinase, and melanocyte [2, 3]
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doi:10.1093/nar/12.9.3917

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restoration of cardiac function after myocardial infarction by long-term activation of the CNS leptin-melanocortin system
