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The AlphaFold2 model also shows reasonable placement of the remaining R-domain segments, including those preceding the start of R-domain model (880900) and part of the R-domain after NBD1 (849-859) consistent with visible electron potential density from our cryo-EM maps
writingreview and editing, M.T.J.H., C.P., P.M., and T.A.L
doi:10.1016/j.jmb.2008.06.083
Studies suggest it seems to bind to p53, perhaps blocking its ability to trigger senescent cell apoptosis [iii]
doi: 10.1161/01.hyp.6.5.736
Sang JH, Ki NK, Cho JH, Ahn JO, Sunwoo JG
