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Overview of CBD safety concerns While CBD shows therapeutic potential, clinical trials and product labels have reported common adverse effects such as gastrointestinal symptoms, fatigue/somnolence, and appetite/weight changes, which are usually dose-related and can improve with dose adjustment (Zhou et al

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It was concluded that small changes in the GSH/GSSG ratio is amplified to large effects on redox potential through the oxidation/reduction of cysteine residues within proteins, rather than changes in the GSH/GSSG ratio directly affecting the cellular redox potential [11]

conceived the project, designed and performed the majority of the experiments, analyzed the data, and wrote the manuscript

10.3389/fnbeh.2019.00204 Front