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Description
Activates ERK1/2 and AKT pathways via growth factor receptor upregulation

Time Point Week 52 What Trials Saw Pooled extension data showed maintained VAT effects with continued therapy

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Their impact is most evident in hepatocellular carcinoma, where they form DNA adducts and induce mutations in the TP53 gene [166]

HPLC and MS/MS validation performed per batch
