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Similarly, Xiangli Zhang and colleagues fabricated a self-powered enzymatic microneedle patch composed of anodic and cathodic microneedle arrays (Fig
Simvastatin treatment significantly reduced total cholesterol, LDL fraction cholesterol, and Hcy concentrations and also increased nitrite concentration (up to 60.9%)

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Oberhelman SS, Meekins ME, Fischer PR, Lee BR, Singh RJ, Cha SS, et al

And this does not even consider that drug metabolizing enzymes in the fetus or newborn are generally lower than in adults
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