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Description
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
Gullner and Komives, 2006)
Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures
Specifically, peptides and proteins that have been denatured or degraded can lead to adverse patient reactions such as undesired immune responses
[PubMed: 31036494] 102
This review emphasises the importance of integrating mechanistic insights and precision medicine approaches to maximise SFNs clinical utility
