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[PubMed] [Google Scholar] Cohen SM, Olin KL, Feuer WJ, Hjelmeland L, Keen CL, Morse LS

Notably, tau protein lactylation at K677 initiates ferroautophagy and ferroptosis through the MAPK pathway, leading to microglial activation and neuroinflammation [82]

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Although Grx are mainly responsible for deglutathionylation reactions, recent evidence has indicated a role for Grx in protein glutathionylation, mediated by the stabilization of a GSH thiyl radical which is then subsequently transferred to an available protein thiol (Starke et al., 2003)