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This combination reduces calorie consumption and supports weight loss efforts

Am J Physiol Gastrointest Liver Physiol 292, G11621172, doi:00441.2006 [pii] 10.1152/ajpgi.00441.2006 (2007)

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It is also recognized as a superordinate, critical hub within the hierarchical structure of cytokine networks underlying various chronic inflammatory diseases (Figure 1)