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On this basis, antioxidants that regulate cellular oxidative stress to treat NIHL by targeting free radicals have been developed [123]

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Anti-cancer drugs such as PTX can exacerbate this effect by inhibiting microtubule dynamics, which are critical for mitochondrial transport and distribution within cells

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pylori can secrete cholesterol--glucosyltransferase (CGT), which inhibits the fusion of autophagosomes with lysosomes, leading to a significant increase in bacterial load within macrophages, thereby impairing the autophagic process of macrophage clearance (Lai et al., 2018)