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Deficiency of a more proximal enzyme in that metabolic pathway, homogentisic acid dioxygenase, the third enzyme, is associated with the medical condition alkaptonuria and the clinical condition is not associated with any hypertyrosinemia

For Adult Use Intended for adult consumption

Lieu PT, Heiskala M, Peterson PA, Yang Y (2001) The roles of iron in health and disease

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K., Kapitsinou, P., Pergola, P

Clinically Relevant Experimental Animal Models Because of the limitations/difficulties related to human studies due to in part to ethical concerns, the use of experimental animal models becomes an important alternative to investigate disease pathogenesis