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Description
As described previously, xCT activity requires obligatory export of glutamate for the import of extracellular cystine
This then allows separation of many compounds that can be identified by their movement on HPLC

Molecular studies utilizing siRNA directed against TGH-2 in 3T3-L1 adipocytes demonstrated a 10% decrease in isoproterenol-stimulated glycerol release, while TGH-2 overexpression was found to increase glycerol release by 20%

A systematic review of Sec24 cargo interactome
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