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PUFAs, particularly AA and adrenergic acid, are susceptible to oxidation owing to the weak C-H bonds in their diallyl group (Kagan et al., 2017)

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In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)
84, 550555 10.1111/j.1751-1097.2007.00242.x [DOI] [PubMed] [Google Scholar] 56.Bouayed J

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