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Voltage-gated Ca 2+ channels Activation of VGCCs at depolarized membrane potentials allows Ca 2+ entry into neurons through the channel pore where it can then influence Ca 2+ -activated K + channels, gene expression, neuronal excitability and firing patterns, and neurotransmitter release

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Supplemental Figure 5E)

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Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19)

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