nrf2 glutathione peroxidase schizophrenia Recent Advances in Understanding Agonism and Its Potential Clinical Application to Metabolic and Inflammatory Diseases Frontiers | Targeting Nrf2 to

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Chattaraj and Paul v

PMID: 27795561

Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007

Cambroll J, Garca JL, Figueroa ME, Cantos M

A recent study on lovastatin for PD treatment demonstrated that lovastatin has stronger bloodbrain barrier penetration compared to other statins, shows potential therapeutic effects on motor symptoms in early-stage PD patients, and exhibits good tolerability [170]