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Meanwhile, studies have shown that GPX4 may be a key downstream target of PIEZO1 (Du et al., 2025)

In the present study, the physicochemical parameters (#H-bond acceptors, #H-bond donors, MR, TPSA, iLOGP, and XLOGP3) were generated using in silico prediction tools and were compared descriptively between phytochemicals of Mucuna pruriens and Ginkgo biloba

FIGURE 3 Furthermore, a thorough mutagenesis study of Md ACO1, identified other important residues essential for ACO activity: C28, T157, K158, R175, Q188, K199, K230, R244, S246, K292, E294, E297, R299, F300, and E301 (Dilley et al., 2013)

Verbal consent was obtained when there were limitations with literacy and the individual expressed a general disinclination to signing written documents that cannot be read and fully comprehended by them

The study was carried out through various computational methods using Autodock Vina for docking of the protein and ligand and Desmond for MD simulation

This acetyl-CoA can be utilized by histone acetyltransferases (HAT) to acetylate histones