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This observation might explain the larger difference in lesion development observed in the abdominal aorta after 24 weeks
In addition, in animals, ASC participates in regulating gene expression, is involved in DNA and histone demethylation, and alters the cell cycle via epigenetic pathways (Blaschke et al., 2013

For example, egl-9 mutants show decreased rates of locomotion and defecation and increased resistance to various stressors, including hypoxia and oxidative stress 18,29,30

This form has been studied for decades and is known to stimulate wound healing, boost antioxidant defenses, and promote collagen/elastin synthesis
