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Expert opinion on investigational drugs, 2009, 18(12): 18931905
[DOI] [PubMed] [Google Scholar] 71.Heisterkamp N., Groffen J., Warburton D., Sneddon T.P
4.2 Prebiotics as critical modulators of gut-thyroid homeostasis Prebiotics, indigestible dietary fibers that selectively stimulate the growth and activity of beneficial gut bacteria, serve as essential adjuncts to probiotic therapy and independently contribute to hypothyroidism management (Ouyang et al., 2024)
A 2025 systematic review in the HSS Journal (Vasireddi et al., PMID 40756949) screened 544 articles on BPC-157 and included 36: 35 preclinical studies and one clinical retrospective
This process relies on signaling pathways such as brain-derived neurotrophic factor (BDNF) and NMDA receptor-mediated synaptic plasticity
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