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doi:10.1111/liv.13009

Author MC was employed by Corium, LLC

Evidence implicating disruption in intestinal barrier functions in the development of many systemic diseases, ranging from non-alcoholic steatohepatitis to autism, or systemic complications of intestinal disorders has increased rapidly in recent years, raising the possibility of the intestinal barrier as a potential target for therapeutic intervention to alter the course and mitigate the complications associated with these diseases

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However, long-term human safety data remains limited, and products sold online are labeled strictly for research use

The first group (the APP/PS1 group) was used as the positive control and comprised APP/PS1 mice with confirmed manifestations of Alzheimers-type pathology