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Maximum plasma concentration and extent of exposure were higher after multiple doses than after a single dose

In murine tumor models, CD40 demonstrates a more pronounced anti-tumor effect over time when compared to CD28 and 4-1BB [72]

Multinodular goiters, particularly those that constrict airways, the esophagus or blood vessels
10.1111/j.1748-1716.2007.01713.x 51 LaursenP
