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PI3K Inhibitor Reversed the Effect of Dihexa in the Brains of APP/PS1 Mice To validate whether the PI3K/AKT signaling pathway is involved in the mechanism of the Dihexa, we detected the number of neuronal cells and the level of SYP and inflammatory factors in the brains of mice after intragastric administration of wortmannin (a PI3K inhibitor)

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doi: 10.1093/nar/gkn778

Biochemistry 40 , 15671576 (2001)

Polyphenols are also explored as adjuncts to conventional therapies due to their neuroprotective properties (Kumari et al

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