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This dual role makes it particularly vulnerable to metabolic stressors and crucial for maintaining redox homeostasis [41, 42]
Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress

Cell Death Dis (2021) 12(9):834

Our body also produces oxalate as waste, it's an end product of some normal metabolic processes

Preclinical studies have shown that ferroptosis-preventing therapies, such as the GSH precursor N-acetylcysteine (NAC), iron-chelating agents like deferoxamine (DFO) and deferiprone (DFP), and specific ferroptosis inhibitors like ferrostatin-1 (Fer-1), can alleviate neurodegeneration and improve motor symptoms in PD animal models ( In this comprehensive review, we aim to summarize the multifaceted roles of ferroptosis in PD pathogenesis, elucidate the links between PD-associated pathogenic proteins and ferroptosis, and provide an overview of current clinical trials and the potential of ferroptosis in the early diagnosis and treatment of PD

Nutrition Research 24: 647-657.CrossRefGoogle Scholar MORAN, E.T
