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Provided herein are modes of treatment for otic formulations or compositions that ameliorate or lessen otic disorders described herein

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Sifalimumab, a human anti-interferon- monoclonal antibody, in systemic lupus erythematosus: a phase 1 randomized controlled, dose-escalation study

A first pass of high drug concentration through this enzyme-laden organ can significantly reduce the quantity of agent reaching the systemic circulation

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Diatom frustules are composed mainly of hydrated SiO 2 tightly bound to peptides and polyamines, forming a species-specific framework with pore diameters of up to 40 nm