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This precise regulation of iron metabolism can prevent iron overload-induced Fenton reactions, thereby inhibiting ferroptosis

Interestingly, in renal clear cell carcinoma, IDO expressed by neovascularization endothelial cells is an inhibitory factor in tumor growth because it limits the flow of tryptophan from the blood to the tumor or produces tumor toxic substances (Riesenberg et al., 2007)

Protects muscles from oxidative stress