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Strikingly, in the mesenteric arterioles, the CBS +/ vessels showed paradoxical vasoconstriction to the endothelium-dependent vasodilators -methacholine and bradykinin rather than the normal vasodilation found in wildtype vessels

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They are typically polar in nature which limits passive diffusion through the lipid membrane

Nanotoxicology 78 , 13021314 (2013)

Thompson SA, White CC, Krejsa CM, et al

Consultation and area assessment
