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6 Future perspectives Metabolomics is to become an important tool in research related to the investigation of drug-induced hepatotoxicity, allowing researchers to assess the deleterious effects of xenobiotics by identifying changes in metabolite levels that uncover the toxic mechanisms at play, the identification of biomarkers of interest suitable for clinical diagnosis and facilitating the development of predictive models

Synthesis, characterization, and multifunctional bioactivity of cadmium oxide-modified graphitic carbon nitride (CdO/G-C3N4) nanocomposites for biomedical applications

10.1167/iovs.17-23402 42 DogruM.MatsumotoY.YamamotoY.GotoE.SaikiM.ShimazakiJ.et al (2007)

In line with such results, also non-toxic digoxin-like synthetic derivatives (20,22-dihydrodigoxin-21,23-diol and digoxin-21-salicylidene) have been shown to specifically block IL-17 expression in human CD4 + T cells by inhibiting RORt activity 141

[DOI] [PubMed] [Google Scholar] 58.Piyathilake C.J., Azrad M., Jhala D., Macaluso M., Kabagambe E.K., Brill I., Niveleau A., Jhala N., Grizzle W.E