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Subsequently, biotin-modified liquid perfluorocarbon NPs, serving as a novel targeted ultrasound contrast agent, significantly enhanced the visualization of thrombosis [191, 192]

The ablation of OPLAH in mouse models has led to an accumulation of 5-OP, which results in oxidative stress, fibrosis, and the continued elevation of pressure due to heart failure [125]

doi: 10.1126/scitranslmed.aaw6635 51 Molina-QuirozR

The serotonergic system is particularly sensitive to stress, and alterations in serotonin signaling can contribute to depressive symptoms

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Altogether, these findings indicate that pregnant women could benefit from preventative riboflavin supplementation as it reduces the risk of iron-deficient anemia 112,122 , however it is not yet in treatment guidelines